| Accelerometer-measured weekend catch-up sleep and incident dementia: A prospective cohort study |
| 論文作者 |
Chen, H; Shen, T; Zhao, MJ; Tong, LS; Lu, GY; Yang, WC; Li, FC; Feng, CW; Zong, G; Tan, X; Huang, TY; Yuan, CZ |
| 期刊/會議名稱 |
ALZHEIMERS & DEMENTIA |
| 論文年度 |
2025 |
| 論文類別 |
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| 摘要 |
INTRODUCTION: Healthy sleep may support cognitive health, but the role of weekend catch-up sleep is unclear. METHODS: Among 83,776 dementia-free UK Biobank participants aged >= 50 years, sleep duration was estimated from 7-day accelerometer data (2013-2015). Weekend catch-up sleep was defined as the weekend-weekday sleep duration difference. Cox regression model was used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) for all-cause dementia associated with weekend catch-up sleep. RESULTS: During follow-up (median: 8.0 years), 713 participants developed all-cause dementia. Compared with <= 0.5 h, HRs for all-cause dementia across catch-up sleep categories were 0.91 (0.74-1.11) for > 0.5-1 h, 0.64 (0.49-0.86) for > 1-1.5 h, 0.84 (0.60-1.16) for > 1.5-2 h, and 0.83 (0.60-1.16) for > 2 h. The association was stronger among participants with weekday sleep < 8 h (HR: 0.49, 0.29-0.81 for > 1-1.5 h) but non-significant in those with >= 8 h (p-interaction = 0.039). DISCUSSION Moderate weekend catch-up sleep was linked to lower dementia risk, especially among individuals with less weekday sleep. |
| 卷 |
21 |
| 影響因子 |
11.1 |
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